ΤΙ. τὸ δὲ τῶν νόσων ὅθεν συνίσταται, δῆλόν που καὶ παντί. τεττάρων γὰρ ὄντων γενῶν ἐξ ὧν συμπέπηγεν τὸ σῶμα, γῆς πυρὸς ὕδατός τε καὶ ἀέρος, τούτων ἡ παρὰ φύσιν πλεονεξία καὶ ἔνδεια καὶ τῆς χώρας μετάστασις ἐξ οἰκείας ἐπʼ ἀλλοτρίαν γιγνομένη, πυρός τε αὖ καὶ τῶν ἑτέρων ἐπειδὴ γένη πλείονα ἑνὸς ὄντα τυγχάνει, τὸ μὴ προσῆκον ἕκαστον ἑαυτῷ προσλαμβάνειν, καὶ πάνθʼ ὅσα τοιαῦτα, στάσεις καὶ νόσους παρέχει· παρὰ φύσιν γὰρ ἑκάστου γιγνομένου καὶ μεθισταμένου θερμαίνεται μὲν ὅσα ἂν πρότερον ψύχηται, ξηρὰ δὲ ὄντα εἰς ὕστερον γίγνεται νοτερά, καὶ κοῦφα δὴ καὶ βαρέα, καὶ πάσας πάντῃ μεταβολὰς δέχεται. μόνως γὰρ δή, φαμέν, ταὐτὸν ταὐτῷ κατὰ ταὐτὸν καὶ ὡσαύτως καὶ ἀνὰ λόγον προσγιγνόμενον καὶ ἀπογιγνόμενον ἐάσει ταὐτὸν ὂν αὑτῷ σῶν καὶ ὑγιὲς μένειν· ὃ δʼ ἂν πλημμελήσῃ τι τούτων ἐκτὸς ἀπιὸν ἢ προσιόν, ἀλλοιότητας παμποικίλας καὶ νόσους φθοράς τε ἀπείρους παρέξεται. δευτέρων δὴ συστάσεων αὖ κατὰ φύσιν συνεστηκυιῶν, δευτέρα κατανόησις νοσημάτων τῷ βουλομένῳ γίγνεται συννοῆσαι. μυελοῦ γὰρ ἐξ ἐκείνων ὀστοῦ τε καὶ σαρκὸς καὶ νεύρου συμπαγέντος, ἔτι τε αἵματος ἄλλον μὲν τρόπον, ἐκ δὲ τῶν αὐτῶν γεγονότος, τῶν μὲν ἄλλων τὰ πλεῖστα ᾗπερ τὰ πρόσθεν, τὰ δὲ μέγιστα τῶν νοσημάτων τῇδε χαλεπὰ συμπέπτωκεν· ὅταν ἀνάπαλιν ἡ γένεσις τούτων πορεύηται, τότε ταῦτα διαφθείρεται. κατὰ φύσιν γὰρ σάρκες μὲν καὶ νεῦρα ἐξ αἵματος γίγνεται, νεῦρον μὲν ἐξ ἰνῶν διὰ τὴν συγγένειαν, σάρκες δὲ ἀπὸ τοῦ παγέντος ὃ πήγνυται χωριζόμενον ἰνῶν· τὸ δὲ ἀπὸ τῶν νεύρων καὶ σαρκῶν ἀπιὸν αὖ γλίσχρον καὶ λιπαρὸν ἅμα μὲν τὴν σάρκα κολλᾷ πρὸς τὴν τῶν ὀστῶν φύσιν αὐτό τε τὸ περὶ τὸν μυελὸν ὀστοῦν τρέφον αὔξει, τὸ δʼ αὖ διὰ τὴν πυκνότητα τῶν ὀστῶν διηθούμενον καθαρώτατον γένος τῶν τριγώνων λειότατόν τε καὶ λιπαρώτατον, λειβόμενον ἀπὸ τῶν ὀστῶν καὶ στάζον, ἄρδει τὸν μυελόν. καὶ κατὰ ταῦτα μὲν γιγνομένων ἑκάστων ὑγίεια συμβαίνει τὰ πολλά· νόσοι δέ, ὅταν ἐναντίως. ὅταν γὰρ τηκομένη σὰρξ ἀνάπαλιν εἰς τὰς φλέβας τὴν τηκεδόνα ἐξιῇ, τότε μετὰ πνεύματος αἷμα πολύ τε καὶ παντοδαπὸν ἐν ταῖς φλεψὶ χρώμασι καὶ πικρότησι ποικιλλόμενον, ἔτι δὲ ὀξείαις καὶ ἁλμυραῖς δυνάμεσι, χολὰς καὶ ἰχῶρας καὶ φλέγματα παντοῖα ἴσχει·
The origin of disease is plain, of course, to everybody. For seeing that there are four elements of which the body is compacted,—earth, fire, water and air,—when, contrary to nature, there occurs either an excess or a deficiency of these elements, or a transference thereof from their native region to an alien region; or again, seeing that fire and the rest have each more than one variety, every time that the body admits an inappropriate variety, then these and all similar occurrences bring about internal disorders and disease. For when any one element suffers a change of condition that is contrary to nature, all its particles that formerly were being cooled become heated, and the dry presently become moist, and the light heavy, and they undergo every variety of change in every respect. For, as we maintain, it is only the addition or subtraction of the same substance from the same substance in the same order and in the same manner and in due proportion which will allow the latter to remain safe and sound in its sameness with itself. But whatsoever oversteps any of these conditions in its going out or its coming in will produce alterations of every variety and countless diseases and corruptions. Again, in the structures which are naturally secondary in order of construction, there is a second class of diseases to be noted by him who has a mind to take cognizance of them. For inasmuch as marrow and bone and flesh and sinew are compacted from the elements,—and blood also is formed from the same constituents, although in a different way,— most of the other maladies come about like those previously described, but the most severe of them have dangerous results for the reason following: whenever the production of these secondary substances proceeds in the reverse direction, then they are corrupted. For in the order of nature flesh and sinews arise from blood, the sinew from the fibrine because of its kindred quality, and flesh from the coagulated substance which coagulates on its separation from the fibrine; and further, the substance which is derived from the sinews and flesh, being viscid and oily, not only glues the flesh to the substance of the bones but also feeds and increases the bone itself which encloses the marrow, while that which is formed of the purest kind of triangles, very smooth and very oily, filters through the density of the bones, and, as it oozes and drips from the bones, moistens the marrow. Now when each of these substances is produced in this order, health as a rule results; but if in the reverse order, disease. For whenever the flesh is decomposed and sends its decomposed matter back again into the veins, then, uniting with the air, the blood in the veins, which is large in volume and of every variety, is diversified by colors and bitter flavors, as well as by sharp and saline properties, and contains bile and serum and phlegm of every sort.
ΤΙ. παλιναίρετα γὰρ πάντα γεγονότα καὶ διεφθαρμένα τό τε αἷμα αὐτὸ πρῶτον διόλλυσι, καὶ αὐτὰ οὐδεμίαν τροφὴν ἔτι τῷ σώματι παρέχοντα φέρεται πάντῃ διὰ τῶν φλεβῶν, τάξιν τῶν κατὰ φύσιν οὐκέτʼ ἴσχοντα περιόδων, ἐχθρὰ μὲν αὐτὰ αὑτοῖς διὰ τὸ μηδεμίαν ἀπόλαυσιν ἑαυτῶν ἔχειν, τῷ συνεστῶτι δὲ τοῦ σώματος καὶ μένοντι κατὰ χώραν πολέμια, διολλύντα καὶ τήκοντα. ὅσον μὲν οὖν ἂν παλαιότατον ὂν τῆς σαρκὸς τακῇ, δύσπεπτον γιγνόμενον μελαίνει μὲν ὑπὸ παλαιᾶς συγκαύσεως, διὰ δὲ τὸ πάντῃ διαβεβρῶσθαι πικρὸν ὂν παντὶ χαλεπὸν προσπίπτει τοῦ σώματος ὅσον ἂν μήπω διεφθαρμένον ᾖ, καὶ τοτὲ μὲν ἀντὶ τῆς πικρότητος ὀξύτητα ἔσχεν τὸ μέλαν χρῶμα, ἀπολεπτυνθέντος μᾶλλον τοῦ πικροῦ, τοτὲ δὲ ἡ πικρότης αὖ βαφεῖσα αἵματι χρῶμα ἔσχεν ἐρυθρώτερον, τοῦ δὲ μέλανος τούτῳ συγκεραννυμένου χλοῶδες· ἔτι δὲ συμμείγνυται ξανθὸν χρῶμα μετὰ τῆς πικρότητος, ὅταν νέα συντακῇ σὰρξ ὑπὸ τοῦ περὶ τὴν φλόγα πυρός. καὶ τὸ μὲν κοινὸν ὄνομα πᾶσιν τούτοις ἤ τινες ἰατρῶν που χολὴν ἐπωνόμασαν, ἢ καί τις ὢν δυνατὸς εἰς πολλὰ μὲν καὶ ἀνόμοια βλέπειν, ὁρᾶν δὲ ἐν αὐτοῖς ἓν γένος ἐνὸν ἄξιον ἐπωνυμίας πᾶσιν· τὰ δʼ ἄλλα ὅσα χολῆς εἴδη λέγεται, κατὰ τὴν χρόαν ἔσχεν λόγον αὐτῶν ἕκαστον ἴδιον. ἰχὼρ δέ, ὁ μὲν αἵματος ὀρὸς πρᾷος, ὁ δὲ μελαίνης χολῆς ὀξείας τε ἄγριος, ὅταν συμμειγνύηται διὰ θερμότητα ἁλμυρᾷ δυνάμει· καλεῖται δὲ ὀξὺ φλέγμα τὸ τοιοῦτον. τὸ δʼ αὖ μετʼ ἀέρος τηκόμενον ἐκ νέας καὶ ἁπαλῆς σαρκός, τούτου δὲ ἀνεμωθέντος καὶ συμπεριληφθέντος ὑπὸ ὑγρότητος, καὶ πομφολύγων συστασῶν ἐκ τοῦ πάθους τούτου καθʼ ἑκάστην μὲν ἀοράτων διὰ σμικρότητα, συναπασῶν δὲ τὸν ὄγκον παρεχομένων ὁρατόν, χρῶμα ἐχουσῶν διὰ τὴν τοῦ ἀφροῦ γένεσιν ἰδεῖν λευκόν, ταύτην πᾶσαν τηκεδόνα ἁπαλῆς σαρκὸς μετὰ πνεύματος συμπλακεῖσαν λευκὸν εἶναι φλέγμα φαμέν. φλέγματος δὲ αὖ νέου συνισταμένου ὀρὸς ἱδρὼς καὶ δάκρυον, ὅσα τε ἄλλα τοιαῦτα σώματα τὸ καθʼ ἡμέραν χεῖται καθαιρόμενα· καὶ ταῦτα μὲν δὴ πάντα νόσων ὄργανα γέγονεν, ὅταν αἷμα μὴ ἐκ τῶν σιτίων καὶ ποτῶν πληθύσῃ κατὰ φύσιν, ἀλλʼ ἐξ ἐναντίων τὸν ὄγκον παρὰ τοὺς τῆς φύσεως λαμβάνῃ νόμους.
For when all the substances become reversed and corrupted, they begin by destroying the blood itself, and then they themselves cease to supply any nourishment to the body; for they move through the veins in all directions and no longer preserve the order of their natural revolutions, being at enmity with themselves because they have no enjoyment of themselves, and being at war also with the established and regular constitution of the body, which they corrupt and dissolve. Therefore all the oldest part of the flesh that is decomposed becomes tough and is blackened by the continued combustion; and because it is eaten away on every side it is bitter, and therefore dangerous in its attack on any part of the body that is not as yet corrupted. And at one time the black matter acquires a sharpness in place of its bitterness, when the bitter substance becomes more diluted; and at another time the bitter substance acquires a redder color through being dipped in blood, while if the black matter is blended with this it turns greenish; and again, whenever new flesh also is decomposed by the fire of the inflammation, a yellow matter is commingled with the bitter substance. To all these humors the general designation “bile” has been given, either by certain physicians or by someone who was capable of surveying a number of dissimilar cases and discerning amongst them one single type worthy to give its name to them all. All the rest that are counted as species of bile have gained their special descriptions in each case from their colors. Serum is of two kinds: one is the mild whey of the blood; the other, being derived from black and acid bile, is malignant whenever it is imbued with a saline quality through the action of heat; and this kind is termed “acid phlegm.” Another kind involves air and is produced by dissolution from new and tender flesh. And when this is inflated and enclosed by a fluid, and when as a result of this process bubbles are formed which individually are invisible because of their small size but in the aggregate form a mass which is visible, and which possess a color which appears white owing to the foam created,—then we describe all this decomposition of tender flesh intermixed with air as “white phlegm.” And the whey of phlegm that is newly formed is “sweat” and “tears,” and all other such humors as pour forth in the daily purgings of the body. And all these are factors in disease, whenever the blood is not replenished naturally from meats and drinks but receives its mass from opposite substances contrary to Nature’s laws.
ΤΙ. διακρινομένης μὲν οὖν ὑπὸ νόσων τῆς σαρκὸς ἑκάστης, μενόντων δὲ τῶν πυθμένων αὐταῖς ἡμίσεια τῆς συμφορᾶς ἡ δύναμις—ἀνάληψιν γὰρ ἔτι μετʼ εὐπετείας ἴσχει— τὸ δὲ δὴ σάρκας ὀστοῖς συνδοῦν ὁπότʼ ἂν νοσήσῃ, καὶ μηκέτι αὐτὸ ἐξ ἰνῶν αἷμα καὶ νεύρων ἀποχωριζόμενον ὀστῷ μὲν τροφή, σαρκὶ δὲ πρὸς ὀστοῦν γίγνηται δεσμός, ἀλλʼ ἐκ λιπαροῦ καὶ λείου καὶ γλίσχρου τραχὺ καὶ ἁλμυρὸν αὐχμῆσαν ὑπὸ κακῆς διαίτης γένηται, τότε ταῦτα πάσχον πᾶν τὸ τοιοῦτον καταψήχεται μὲν αὐτὸ πάλιν ὑπὸ τὰς σάρκας καὶ τὰ νεῦρα, ἀφιστάμενον ἀπὸ τῶν ὀστῶν, αἱ δʼ ἐκ τῶν ῥιζῶν συνεκπίπτουσαι τά τε νεῦρα γυμνὰ καταλείπουσι καὶ μεστὰ ἅλμης· αὐταὶ δὲ πάλιν εἰς τὴν αἵματος φορὰν ἐμπεσοῦσαι τὰ πρόσθεν ῥηθέντα νοσήματα πλείω ποιοῦσιν. χαλεπῶν δὲ τούτων περὶ τὰ σώματα παθημάτων γιγνομένων μείζω ἔτι γίγνεται τὰ πρὸ τούτων, ὅταν ὀστοῦν διὰ πυκνότητα σαρκὸς ἀναπνοὴν μὴ λαμβάνον ἱκανήν, ὑπʼ εὐρῶτος θερμαινόμενον, σφακελίσαν μήτε τὴν τροφὴν καταδέχηται πάλιν τε αὐτὸ εἰς ἐκείνην ἐναντίως ἴῃ ψηχόμενον, ἡ δʼ εἰς σάρκας, σὰρξ δὲ εἰς αἷμα ἐμπίπτουσα τραχύτερα πάντα τῶν πρόσθεν τὰ νοσήματα ἀπεργάζηται· τὸ δʼ ἔσχατον πάντων, ὅταν ἡ τοῦ μυελοῦ φύσις ἀπʼ ἐνδείας ἤ τινος ὑπερβολῆς νοσήσῃ, τὰ μέγιστα καὶ κυριώτατα πρὸς θάνατον τῶν νοσημάτων ἀποτελεῖ, πάσης ἀνάπαλιν τῆς τοῦ σώματος φύσεως ἐξ ἀνάγκης ῥυείσης. τρίτον δʼ αὖ νοσημάτων εἶδος τριχῇ δεῖ διανοεῖσθαι γιγνόμενον, τὸ μὲν ὑπὸ πνεύματος, τὸ δὲ φλέγματος, τὸ δὲ χολῆς. ὅταν μὲν γὰρ ὁ τῶν πνευμάτων τῷ σώματι ταμίας πλεύμων μὴ καθαρὰς παρέχῃ τὰς διεξόδους ὑπὸ ῥευμάτων φραχθείς, ἔνθα μὲν οὐκ ἰόν, ἔνθα δὲ πλεῖον ἢ τὸ προσῆκον πνεῦμα εἰσιὸν τὰ μὲν οὐ τυγχάνοντα ἀναψυχῆς σήπει, τὰ δὲ τῶν φλεβῶν διαβιαζόμενον καὶ συνεπιστρέφον αὐτὰ τῆκόν τε τὸ σῶμα εἰς τὸ μέσον αὐτοῦ διάφραγμά τʼ ἴσχον ἐναπολαμβάνεται, καὶ μυρία δὴ νοσήματα ἐκ τούτων ἀλγεινὰ μετὰ πλήθους ἱδρῶτος πολλάκις ἀπείργασται. πολλάκις δʼ ἐν τῷ σώματι διακριθείσης σαρκὸς πνεῦμα ἐγγενόμενον καὶ ἀδυνατοῦν ἔξω πορευθῆναι τὰς αὐτὰς τοῖς ἐπεισεληλυθόσιν ὠδῖνας παρέσχεν, μεγίστας δέ, ὅταν περὶ τὰ νεῦρα καὶ τὰ ταύτῃ φλέβια περιστὰν καὶ ἀνοιδῆσαν τούς τε ἐπιτόνους καὶ τὰ συνεχῆ νεῦρα οὕτως εἰς τὸ ἐξόπισθεν κατατείνῃ τούτοις· ἃ δὴ καὶ ἀπʼ αὐτοῦ τῆς συντονίας τοῦ παθήματος τὰ νοσήματα τέτανοί τε καὶ ὀπισθότονοι προσερρήθησαν.
Now, when the flesh in any part is being decomposed by disease, but the bases thereof still remain firm, the force of the attack is reduced by half, for it still admits of easy recovery; but whenever the substance which binds the flesh to the bones becomes diseased and no longer separates itself at once from them and from the sinews, so as to provide food for the bone and to serve as a bond between flesh and bone, but becomes rough and saline instead of being oily and smooth and viscid, owing to its being starved by a bad regimen,—then, every such substance, as it undergoes these affections, molders away beneath the flesh and the sinews and withdraws from the bones; while the flesh falls away with it from the roots and leaves the sinews bare and full of saline matter, and by falling back itself into the stream of the blood it augments the maladies previously described. But although these bodily ailments are severe, still more grave are those which precede them, whenever the bone by reason of the density of the flesh fails to receive sufficient inspiration, and becoming heated because of its moldiness decays and does not admit its nutriment, but, on the contrary, falls back itself, as it crumbles, into its nutriment which then passes into flesh, and this flesh falling into, the blood causes all such maladies to be more violent than those previously described. And the most extreme case of all occurs whenever the substance of the marrow becomes diseased either from deficiency or from excess; for this results in the gravest of diseases and the most potent in causing death, inasmuch as the whole substance of the body, by the force of necessity, streams in the reverse direction. A third class of diseases takes place, as we must conceive, in three ways, being due partly to air, partly to phlegm, and partly to bile. Whenever the lungs, which are the dispensers of air to the body, fail to keep their outlets clean through being blocked up with rheums, then the air, being unable to pass one way while entering by another way in more than its proper volume, causes the parts deprived of respiration to rot, but forces and distorts the vessels of the veins, and as it thus dissolves the body it is itself shut off within the center thereof which contains the midriff; and as a result of this countless diseases of a painful kind are produced, accompanied by much sweating. And often, when the flesh is disintegrated, air which is enclosed in the body and is unable to pass out brings about the same pangs as those caused by the air that enters from without; and these pangs are most severe when the air surrounds the sinews and the adjacent veins and by its swelling up strains backwards the tendons and the sinews attached to them; hence it is actually from this process of intense strain that these maladies have derived their names of “tetanus” and “opisthotonus.”
ΤΙ. ὧν καὶ τὸ φάρμακον χαλεπόν· πυρετοὶ γὰρ οὖν δὴ τὰ τοιαῦτα ἐπιγιγνόμενοι μάλιστα λύουσιν. τὸ δὲ λευκὸν φλέγμα διὰ τὸ τῶν πομφολύγων πνεῦμα χαλεπὸν ἀποληφθέν, ἔξω δὲ τοῦ σώματος ἀναπνοὰς ἴσχον ἠπιώτερον μέν, καταποικίλλει δὲ τὸ σῶμα λεύκας ἀλφούς τε καὶ τὰ τούτων συγγενῆ νοσήματα ἀποτίκτον. μετὰ χολῆς δὲ μελαίνης κερασθὲν ἐπὶ τὰς περιόδους τε τὰς ἐν τῇ κεφαλῇ θειοτάτας οὔσας ἐπισκεδαννύμενον καὶ συνταράττον αὐτάς, καθʼ ὕπνον μὲν ἰὸν πρᾳΰτερον, ἐγρηγορόσιν δὲ ἐπιτιθέμενον δυσαπαλλακτότερον· νόσημα δὲ ἱερᾶς ὂν φύσεως ἐνδικώτατα ἱερὸν λέγεται. φλέγμα δʼ ὀξὺ καὶ ἁλμυρὸν πηγὴ πάντων νοσημάτων ὅσα γίγνεται καταρροϊκά· διὰ δὲ τοὺς τόπους εἰς οὓς ῥεῖ παντοδαποὺς ὄντας παντοῖα ὀνόματα εἴληφεν. ὅσα δὲ φλεγμαίνειν λέγεται τοῦ σώματος, ἀπὸ τοῦ κάεσθαί τε καὶ φλέγεσθαι, διὰ χολὴν γέγονε πάντα. λαμβάνουσα μὲν οὖν ἀναπνοὴν ἔξω παντοῖα ἀναπέμπει φύματα ζέουσα, καθειργνυμένη δʼ ἐντὸς πυρίκαυτα νοσήματα πολλὰ ἐμποιεῖ, μέγιστον δέ, ὅταν αἵματι καθαρῷ συγκερασθεῖσα τὸ τῶν ἰνῶν γένος ἐκ τῆς ἑαυτῶν διαφορῇ τάξεως, αἳ διεσπάρησαν μὲν εἰς αἷμα, ἵνα συμμέτρως λεπτότητος ἴσχοι καὶ πάχους καὶ μήτε διὰ θερμότητα ὡς ὑγρὸν ἐκ μανοῦ τοῦ σώματος ἐκρέοι, μήτʼ αὖ πυκνότερον δυσκίνητον ὂν μόλις ἀναστρέφοιτο ἐν ταῖς φλεψίν. καιρὸν δὴ τούτων ἶνες τῇ τῆς φύσεως γενέσει φυλάττουσιν· ἃς ὅταν τις καὶ τεθνεῶτος αἵματος ἐν ψύξει τε ὄντος πρὸς ἀλλήλας συναγάγῃ, διαχεῖται πᾶν τὸ λοιπὸν αἷμα, ἐαθεῖσαι δὲ ταχὺ μετὰ τοῦ περιεστῶτος αὐτὸ ψύχους συμπηγνύασιν. ταύτην δὴ τὴν δύναμιν ἐχουσῶν ἰνῶν ἐν αἵματι χολὴ φύσει παλαιὸν αἷμα γεγονυῖα καὶ πάλιν ἐκ τῶν σαρκῶν εἰς τοῦτο τετηκυῖα, θερμὴ καὶ ὑγρὰ κατʼ ὀλίγον τὸ πρῶτον ἐμπίπτουσα πήγνυται διὰ τὴν τῶν ἰνῶν δύναμιν, πηγνυμένη δὲ καὶ βίᾳ κατασβεννυμένη χειμῶνα καὶ τρόμον ἐντὸς παρέχει.
Of these maladies the cure also is severe for what does most to relieve them is, in fact, an attack of fever. White phlegm, also, is dangerous when it is blocked inside because of the air in its bubbles; but when it has air-vents outside the body it is milder, although it marks the body with spots by breeding white scabs and tetters and the maladies akin thereto. And when this phlegm is blended with black bile and spreads over the revolutions of the head, which are the most divine, and perturbs them, its action is more gentle during sleep, but when it attacks persons who are awake it is harder to shake off; and because it is a disease of the sacred substance it is most justly termed “the sacred disease.” Phlegm that is sharp and saline is the fount of all the maladies which are of the nature of catarrhs; and these have received all kinds of names because the regions into which they flow are of all varieties. All those diseases which are called inflammations, owing to the burning and inflaming of the body which they involve, are caused by bile. This, when it gains an external outlet, boils and sends up all kinds of eruptions; but when it is confined inside it produces many burning diseases; and of these the gravest occurs when the bile, being mixed with pure blood, displaces the matter of the fibrine from its proper position. For this fibrine is dispersed through the blood in order that the blood may have a due proportion of both rarity and density, and may neither flow out from the porous body through being liquefied by heat, nor yet prove immobile through its density and circulate with difficulty in the veins. Of these qualities the fibrine preserves the due amount owing to the nature of its formation. Even when anyone collects together the fibrine of blood that is dead and in process of cooling, all the rest of the blood turns liquid; but if the fibrine is left alone as it is, it acts in combination with the surrounding cold and rapidly congeals the blood. As the fibrine, then, has this property, bile, which is naturally formed of old blood and dissolved again into blood from flesh, penetrates the blood gradually at first, while it is hot and moist, and is congealed by this property of the fibrine; and as it becomes congealed and forcibly chilled it causes internal cold and shivering.