Pandora was the first female on earth, she was called "beautiful evil". She was a punishment for the mankind (especially for Prometheus) for stealing the fire from the gods of Olympus. She was made of clay by Hefaistos and send down on the earth with a jar (not a box, a jar, originally). Her lover Ephimetheus told her not to open the jar, but her curiosity won and she opened it. Doing so she released all the suffering and plagues to the world, and it was all ready late when she tried to close it. Only thing that stayed in the jar was hope. What was hope doing in the jar of unhappiness? Is it ´cos hope is kinda an illusion that you can control the future? Anyway, when Pandora opened the jar again, hope was released too.