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Echidna of Arima, wife of Typhon. She is among the most infamous of the Phorcydes, the children of Phorcys and Ceto.
Her epithet, "Mother of Monsters," is quite well-earned, as her children by Typhon, and according to Hesiod, by her son, the two-headed hound, Orthrus, were among the most famous monsters of Greek Mythology.

Besides Orthrus, a few of Echidna's better known spawn included the Hydra, Cerberus, the Chimera, the Nemean Lion, and the Teumessian Vixen.
Cancer
Iris
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Hera